David Mutch

Associate Professor College of Biological Science Department of Human Health and Nutritional Sciences Guelph, Ontario dmutch@uoguelph.ca Office: (519) 824-4120 ext. 53322

Bio/Research

Over the past thirty years the prevalence of both adult and childhood obesity has steadily increased to epidemic proportions. Lifestyle interventions (i.e. caloric restriction and increased physical activity) remain the most common recommendation for controlling obesity; however, the rate of succ...

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Bio/Research

Over the past thirty years the prevalence of both adult and childhood obesity has steadily increased to epidemic proportions. Lifestyle interventions (i.e. caloric restriction and increased physical activity) remain the most common recommendation for controlling obesity; however, the rate of success is wholly dependent on the individual. As such, alternate approaches must be considered and tested if we are to turn the tide in our fight against obesity. Nutrigenomics is poised to have a considerable impact on the prevention and treatment of obesity by recommending lifestyle modifications based on an individual’s genetic information.

My research program is focused on understanding how dietary lipids can affect adipose tissue function using several modern approaches such as: 1) Genetics - to determine whether polymorphisms in genes involved in lipid metabolism are associated with obesity-related phenotypes, 2) Transcriptomics - to elucidate how different dietary lipids affect gene expression and function, and 3) Metabolomics - to identify novel biomarkers that can be used to assess the efficacy of dietary interventions in order to better personalize health management. Integrating these approaches will provide additional information to help understand why individuals respond differentially to dietary interventions.


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Media Relations

Lori Bona Hunt
l.hunt@exec.uoguelph.ca
519-824-4120 ext. 53338

Kevin Gonsalves
kgonsalves@uoguelph.ca
519-824-4120 ext. 56982