Marc Coppolino

Adjunct Professor College of Biological Science Department of Molecular and Cellular Biology Guelph, Ontario mcoppoli@uoguelph.ca Office: (519) 824-4120 ext. 53031

Bio/Research

Cell adhesion and migration are fundamentally important to the existence of multicellular organisms. This is obvious in light of the numerous diseases that can afflict humans when these processes are impaired. Disruption of normal cellular adhesive and migratory activities can lead to development...

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Bio/Research

Cell adhesion and migration are fundamentally important to the existence of multicellular organisms. This is obvious in light of the numerous diseases that can afflict humans when these processes are impaired. Disruption of normal cellular adhesive and migratory activities can lead to developmental disorders and contribute to the progression of arthritis, immunological deficiencies and cancer. Both cell adhesion and migration are complex processes involving numerous biochemical signalling events, reorganization of the cellular cytoskeleton and localized remodelling of the plasma membrane. It is the goal of my laboratory to elucidate the molecular mechanisms that link these activities, allowing them to be coordinated during changes in cell adhesion and motility.

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Lori Bona Hunt
l.hunt@exec.uoguelph.ca
519-824-4120 ext. 53338