Shaun Sanders
Assistant Professor College of Biological Science Department of Molecular and Cellular Biology Guelph, Ontario ssande03@uoguelph.ca
Bio/Research
The Sanders lab is a molecular neuroscience lab interested in how neurons use the protein-lipid modification palmitoylation to target proteins to specific subcellular locations in and to define how palmitoylation-dependent targeting contributes to physiological neuronal function and neuropatholog...
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Bio/Research
The Sanders lab is a molecular neuroscience lab interested in how neurons use the protein-lipid modification palmitoylation to target proteins to specific subcellular locations in and to define how palmitoylation-dependent targeting contributes to physiological neuronal function and neuropathological conditions.
Our lab is particularly interested in how palmitoylation of ion channels and trafficking machinery regulates sub-neuronal targeting of proteins and, in turn, neuronal function.
We use cutting edge genetic, biochemical, and cell biological approaches to answer these questions, including CRISPR-mediated gene knockout and mutation, shRNA-mediated knockdown and rescue, specialized palmitoylation assays, and live and fixed confocal microscopy in neurons grown in conventional culture and in microfluidic devices.
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Our lab is particularly interested in how palmitoylation of ion channels and trafficking machinery regulates sub-neuronal targeting of proteins and, in turn, neuronal function.
We use cutting edge genetic, biochemical, and cell biological approaches to answer these questions, including CRISPR-mediated gene knockout and mutation, shRNA-mediated knockdown and rescue, specialized palmitoylation assays, and live and fixed confocal microscopy in neurons grown in conventional culture and in microfluidic devices.
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Links
Media Relations
Media Relations
Lori Bona Hunt
l.hunt@exec.uoguelph.ca
519-824-4120 ext. 53338
Deirdre Healey
healeyd@uoguelph.ca
519-824-4120 ext. 56581
Angela Mulholland
angela.mulholland@uoguelph.ca
519-824-4120 ext. 56982
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l.hunt@exec.uoguelph.ca
519-824-4120 ext. 53338
Deirdre Healey
healeyd@uoguelph.ca
519-824-4120 ext. 56581
Angela Mulholland
angela.mulholland@uoguelph.ca
519-824-4120 ext. 56982
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